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June 1, 1984Anesthesia & Analgesia

Comparison of Intramuscular and Epidural Morphine for Postoperative Analgesia in the Grossly Obese

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Why the study?

Does epidural morphine improve postoperative analgesia and recovery compared to intramuscular morphine in grossly obese patients undergoing gastroplasty?

Population

30 grossly obese patients undergoing gastroplasty for weight reduction

Comparison

Epidural morphine vs Intramuscular morphine

Design

RCT, randomized, double-blind

Follow-up

until hospital discharge

Authors

NRNarinder RawalÖrebro UniversityUSU. SjöstrandLinköping UniversityECE ChristofferssonSahlgrenska University Hospital

Discussion

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Overview

Supports epidural morphine preference in obese gastroplasty patients; extends RCT evidence for neuraxial over systemic opioids in bariatric surgery.

Structured PICO

Does epidural morphine improve postoperative analgesia and recovery compared to intramuscular morphine in grossly obese patients undergoing gastroplasty?

P
Population
30 grossly obese patients undergoing gastroplasty for weight reduction
I
Intervention
Epidural morphine
C
Comparator
Intramuscular morphine
O
Outcome
Postoperative analgesia

Epidural morphine offers superior analgesia and facilitates faster postoperative recovery compared to intramuscular morphine in obese patients undergoing gastroplasty.

Cite This Study

Rawal et al. (1984) studied this question.

synapsesocial.com/papers/6a86edbf4a47ef1dc7d3bae7https://doi.org/10.1213/00000539-198406000-00006
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Postoperative Analgesia and Lung Function: a Comparison of Intramuscular with Epidural Morphine1982 · 46 citations
  2. 2A Controlled Study on the Effect of Epidural Analgesia with Local Anaesthetics and Morphine on Morbidity after Abdominal Surgery1985 · 139 citations
  3. 3Morphine Plus Bupivacaine Vs. MorphinePeridural Analgesia in Abdominal Surgery:The Effects on Postoperative Coursein Major Hepatobiliary Surgery1998 · 13 citations
  4. 4Pain relief and safety after major surgery A prospective study of epidural and intravenous analgesia in 2696 patients2003 · 106 citations
  5. 5Intrathecal Morphine in Major Abdominal and Thoracic Surgery: Observational Study2025 · 3 citations