Why the study?
Does pregnancy alter the fibrinolytic response to venous occlusion and D-dimer levels compared to the non-pregnant state?
Does pregnancy alter the fibrinolytic response to venous occlusion and D-dimer levels compared to the non-pregnant state?
Despite a marked impairment in t-PA release following venous occlusion during pregnancy, elevated D-dimer levels suggest the fibrinolytic system remains functionally active.
No takes yet. Share an insight, caveat, or question.
Reduced t-PA release in pregnancy does not necessarily indicate fibrinolytic impairment; leaves open compensatory mechanisms reflected by increased D-dimer levels.
Ballegeer et al. (1987) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: