Why the study?
Does insulin-induced hypoglycemia elicit different pancreatic polypeptide and catecholamine responses in patients with chronic autonomic failure compared to healthy subjects?
Population
15 patients with neurogenic orthostatic hypotension and 11 healthy subjects
Comparison
Insulin-induced hypoglycemia vs Healthy subjects
Design
Case-control
Authors
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Patients with chronic autonomic failure have impaired pancreatic polypeptide responses to hypoglycemia, suggesting diffuse autonomic dysfunction involving both parasympathetic and sympathetic nervous systems.
Does insulin-induced hypoglycemia elicit different pancreatic polypeptide and catecholamine responses in patients with chronic autonomic failure compared to healthy subjects?
Patients with chronic autonomic failure have impaired pancreatic polypeptide responses to hypoglycemia, suggesting diffuse autonomic dysfunction involving both parasympathetic and sympathetic nervous systems.
Polinsky et al. (1982) studied this question.
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