Why the study?
Does intravenous infusion of epinephrine affect coronary circulation differently in human subjects with and without coronary artery disease?
Population
21 human subjects, 8 with and 13 without coronary artery disease
Comparison
Intravenous infusion of epinephrine vs Subjects without coronary artery disease
Design
Other
Authors
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Epinephrine may augment coronary flow via metabolic demand similarly in CAD and non-CAD; leaves open modern randomized confirmation.
Does intravenous infusion of epinephrine affect coronary circulation differently in human subjects with and without coronary artery disease?
Intravenous epinephrine increases coronary flow secondary to augmented myocardial metabolic demands, with similar physiological effects in patients with and without coronary artery disease.
Sullivan et al. (1967) studied this question.
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