Population
Acutely dissociated adult rat ventricular myocytes
Comparison
High cell density culture / direct cell-cell… vs Low cell density culture / conditioned culture…
Design
Preclinical
Follow-up
3 hours
Authors
Loading...
Cell density effects on Kv expression in adult myocytes warrant no clinical extrapolation; leaves open in vivo roles in repolarization and arrhythmogenesis.
Direct cell-cell contact between adult cardiac myocytes reciprocally regulates the mRNA expression of Kv1.5 and Kv4.2 potassium channels.
Hershman et al. (1998) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: