Population
Hepatitis C virus (HCV) internal ribosome entry site (IRES) subdomain IIa
Design
Preclinical
Authors
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May guide structure-based HCV IRES inhibitor design; leaves open functional validation and therapeutic translation.
The determination of the crystal structure of HCV IRES subdomain IIa provides a basis for structure-guided design of HCV translation inhibitors.
Zhao et al. (2008) studied this question.
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