Value of exercise echocardiography in heart failure with preserved ejection fraction: a substudy from the KaRen study
Why the study?
Does exercise echocardiography provide independent prognostic value for death or heart failure hospitalization in patients with HFpEF?
Population
60 patients with heart failure and preserved ejection fraction following an acute HF episode, recruited in a…
Comparison
Submaximal exercise stress echocardiography vs Resting echocardiography
Design
Cohort, Echocardiographic analysis blinded to patients' clinical status and…
Authors
Discussion
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Member takes
Implication
May support exercise TR velocity for HFpEF risk stratification; leaves open whether exercise echo should guide therapy.
Structured PICO
Does exercise echocardiography provide independent prognostic value for death or heart failure hospitalization in patients with HFpEF?
P
Population
60 patients with heart failure and preserved ejection fraction (LVEF > 45%, NT-pro-BNP > 300 pg/mL or BNP > 100 pg/mL) following an acute HF episode, recruited in a single tertiary centre.
I
Intervention
Submaximal exercise stress echocardiography
C
Comparator
Resting echocardiography
O
Outcome
Death or hospitalization for heart failurecomposite
Exercise echocardiography, specifically tricuspid regurgitation peak velocity during exercise, provides independent prognostic value for death or heart failure hospitalization in patients with HFpEF.
Cite This Study
Donal et al. (2015) studied this question.