Population
Normal heart model (specific species not stated in abstract)
Comparison
Graded venous pressure elevations vs Control conditions
Design
Preclinical
Authors
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Interstitial pressure rise limits edema in normal heart; leaves open translation to human cardiac pathophysiology.
The normal heart relies on a large increase in interstitial hydrostatic pressure to limit edema formation during extravascular volume expansion.
Laine et al. (1985) studied this question.
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