Why the study?
Cardiovascular autonomic neuropathy impairs cardiovascular autonomic control in diabetes, and this study aimed to investigate the relationship between glycemic variability and cardiovascular autonomic neuropathy in pediatric patients with type 1 DM.
Is glycemic variability associated with cardiovascular autonomic neuropathy in pediatric patients with type 1 diabetes mellitus?
Population
21 pediatric patients aged 8-18 with type 1 DM
Comparison
Patients with definitive CAN vs those without CAN
Design
Observational study
Authors
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Glycemic variability may signal CAN risk in pediatric T1DM; leaves open whether targeting variability prevents neuropathy.
Is glycemic variability associated with cardiovascular autonomic neuropathy in pediatric patients with type 1 diabetes mellitus?
In pediatric patients with type 1 diabetes, higher glycemic variability (lower time in range and higher time above range) is significantly associated with definitive cardiovascular autonomic neuropathy.
Yılmaz et al. (2023) studied this question.
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