Population
male and female dystrophic C57BL/10J mdx/mdx mice
Comparison
Transplantation of myoblasts from donors… vs Transplantation of myoblasts from syngeneic donors
Design
Preclinical
Follow-up
up to 16 weeks
Authors
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Non-MHC antigens may drive myoblast rejection in mice; leaves open MHC-matching strategies for human cell therapy.
Non-major histocompatibility complex antigens, including minor antigens like H-Y, can trigger cellular immune rejection of transplanted myoblasts in mice.
Boulanger et al. (1997) studied this question.
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