Population
Perfused rat hearts
Comparison
Ischemic preconditioning with or without the PKC… vs No ischemic preconditioning
Design
Preclinical
Authors
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Supports PKC-targeted cardioprotection research; leaves open translation from animal models to clinical practice.
Ischemic preconditioning protects the myocardium and improves LVDP recovery via the translocation of PKC-alpha, delta, and epsilon isoforms to the cell membrane.
Yoshida et al. (1997) studied this question.
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