Comparisons of the immunological properties of two structural polypeptides of type C RNA viruses endogenous to old world monkeys
Population
Type C RNA viruses endogenous to the domestic cat and baboon, and normal rhesus monkey tissues
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Findings remain preclinical and should not guide diagnostics; extends evidence of differential antigenic evolution in endogenous primate viruses.
Structured PICO
P
Population
Type C RNA viruses endogenous to the domestic cat and baboon (old world primate), and normal rhesus monkey tissues
I
Intervention
Radioimmunological techniques for detection of 15,000 and 30,000 molecular weight (MW) polypeptides
O
Outcome
Detection and differentiation of viral polypeptides based on antigenic determinantssurrogate
The immunological properties of two structural polypeptides of closely related viruses endogenous to primate and feline species have undergone different rates of antigenic change in the course of evolution.
Cite This Study
Stephenson et al. (1976) studied this question.