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February 1, 1974Journal of VirologyOpen Access

Primate and Murine Type-C Viral Nucleic Acid Association Kinetics: Analysis of Model Systems and Natural Tissues

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Population

DNA from a variety of uninfected primate species

Design

Preclinical

Authors

ESEdward M. ScolnickBroad InstituteWPWade P. ParksUniversity of PittsburghTKThomas G. KawakamiVeterinary Medical Teaching Hospital

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Implication

No homologous sequences in uninfected primates leaves open exogenous acquisition of type-C viruses; hypothesis-generating for primate epidemiology.

Structured PICO

P
Population
DNA from a variety of uninfected primate species
I
Intervention
Hybridization studies employing single-stranded (3)H-DNA transcripts of type-C viruses isolated from a woolly monkey or gibbon ape
O
Outcome
Detection of nucleic acid sequences homologous to type-C viruses

The study found no homologous type-C viral nucleic acid sequences in uninfected primate species, informing the epidemiology of type-C viruses in primates.

Cite This Study

Scolnick et al. (1974) studied this question.

synapsesocial.com/papers/6a87e4c83bdf89560ead38d5https://doi.org/10.1128/jvi.13.2.363-369.1974
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