Population
Anesthetized rats stressed by specific alternation of rhythm in temperature (SART) and unstressed rats
Comparison
Beta-adrenoceptor blocking agents… vs Unstressed rats
Design
Preclinical
Follow-up
4 min
Authors
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No immediate clinical implications; extends preclinical evidence on beta2-adrenoceptor roles in stress-induced orthostatic reflexes.
In SART-stressed rats, beta1-adrenoceptors play a role in compensatory tachycardia reflex and beta2-adrenoceptors in blood pressure reflex during orthostatic hypotension.
Funakami et al. (2007) studied this question.
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