January 1, 1985Anesthesia & Analgesia

Anesthetic Induction with Fentanyl

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Why the study?

Does fentanyl 30 μg/kg effectively and safely induce anesthesia in ASA I-III patients scheduled for 2-4 hour operations?

Population

72 ASA I–III patients scheduled for 2–4-hr operations

Comparison

Fentanyl 30 μg/kg as an anesthetic induction… vs Different preinduction pretreatments

Design

Cohort

Follow-up

postoperative period

Authors

PBPeter L. BaileyUniversity of Bristol JWJohan WilbrinkUniversity of Utah PZPrisca ZwanikkenRoyal Tropical Institute

Discussion

Member takes

Implication

Fentanyl 30 μg/kg induction remains unreliable below age 60 and is associated with adverse effects; leaves open whether age-stratified regimens warrant prospective trials.

Structured PICO

Does fentanyl 30 μg/kg effectively and safely induce anesthesia in ASA I-III patients scheduled for 2-4 hour operations?

Population

72 ASA I–III patients scheduled for 2–4-hr operations

Intervention

Fentanyl 30 μg/kg as an anesthetic induction agent, with or without preinduction pretreatment with pancuronium and/or diazepam

Comparator

Different preinduction pretreatments (pancuronium alone, diazepam alone, pancuronium plus diazepam, or none)

Outcome

Incidence of loss of consciousness (anesthesia)

Fentanyl 30 μg/kg is not a reliable anesthetic induction dose for patients under 60 years old and is associated with rigidity and postoperative respiratory depression.

Cite This Study

Bailey et al. (1985) studied this question.

synapsesocial.com/papers/6a87fe53010a27dee476ed97 https://doi.org/10.1213/00000539-198501000-00010

View Full Paper

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January 1, 1985Anesthesia & Analgesia

Anesthetic Induction with Fentanyl

View Full Paper

Ask AI

Bookmark

Why the study?

Does fentanyl 30 μg/kg effectively and safely induce anesthesia in ASA I-III patients scheduled for 2-4 hour operations?

Population

72 ASA I–III patients scheduled for 2–4-hr operations

Comparison

Fentanyl 30 μg/kg as an anesthetic induction… vs Different preinduction pretreatments

Design

Cohort

Follow-up

postoperative period

Authors

PBPeter L. BaileyUniversity of Bristol JWJohan WilbrinkUniversity of Utah PZPrisca ZwanikkenRoyal Tropical Institute

Discussion

Member takes

Implication

Fentanyl 30 μg/kg induction remains unreliable below age 60 and is associated with adverse effects; leaves open whether age-stratified regimens warrant prospective trials.

Structured PICO

Does fentanyl 30 μg/kg effectively and safely induce anesthesia in ASA I-III patients scheduled for 2-4 hour operations?

Population

72 ASA I–III patients scheduled for 2–4-hr operations

Intervention

Fentanyl 30 μg/kg as an anesthetic induction agent, with or without preinduction pretreatment with pancuronium and/or diazepam

Comparator

Different preinduction pretreatments (pancuronium alone, diazepam alone, pancuronium plus diazepam, or none)

Outcome

Incidence of loss of consciousness (anesthesia)

Fentanyl 30 μg/kg is not a reliable anesthetic induction dose for patients under 60 years old and is associated with rigidity and postoperative respiratory depression.

Cite This Study

Bailey et al. (1985) studied this question.

synapsesocial.com/papers/6a87fe53010a27dee476ed97 https://doi.org/10.1213/00000539-198501000-00010

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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