Population
Sf9 and Tn5 cells infected with baculovirus recombinants expressing Hepatitis E virus (HEV) capsid proteins
Design
Preclinical
Authors
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Maps essential ORF2 residues for HEV VLP initiation; leaves open utility as mucosal vaccine carriers pending in vivo validation.
Identification of the essential amino acid residues for HEV VLP assembly provides foundational knowledge for constructing recombinant HEV VLPs as potential mucosal vaccine carriers or gene delivery vectors.
Li et al. (2005) studied this question.
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