Population
Rat nervous system
Comparison
Identification and characterization of erg 2 and… vs erg 1 (HERG) gene
Design
Preclinical
Authors
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Does not alter LQT2 management; leaves open whether neural erg channels contribute to sympathetic arrhythmogenesis.
The discovery of erg 2 and erg 3 genes and the expression of erg 1 in the sympathetic nervous system may have implications for understanding the etiology of LQT2 long QT syndrome.
Shi et al. (1997) studied this question.
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