February 13, 2008Journal of Cardiovascular Electrophysiology

Time‐Dependence of Appropriate Implantable Defibrillator Therapy in Patients with Ischemic Cardiomyopathy

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Why the study?

Does the risk of appropriate ICD therapy persist over time in primary prevention patients with prior MI and LVEF ≤35%?

Population

525 patients with prior myocardial infarction and reduced left ventricular ejection fraction who received an…

Design

Cohort

Follow-up

up to 7 years

Authors

AAAlawi Alsheikh‐AliElectrophysiology MHMichael HomerReproductive Science Center PMPrasad MaddukuriSaint Vincent Hospital

Discussion

Member takes

Implication

Risk persists at 6-11% yearly beyond year 1 in ischemic cardiomyopathy; leaves open whether findings justify routine generator replacement.

Structured PICO

Does the risk of appropriate ICD therapy persist over time in primary prevention patients with prior MI and LVEF ≤35%?

Population

525 patients with prior myocardial infarction (MI) and reduced left ventricular ejection fraction (LVEF ≤35%) who received an implantable cardioverter-defibrillator (ICD) for primary prevention in routine clinical practice.

Intervention

Implantable cardioverter-defibrillator (ICD) for primary prevention

Outcome

Incidence and time-dependence of first appropriate ICD therapy for ventricular arrhythmia (VA) and rapid VA (cycle length ≤260 ms)hard clinical

The risk of appropriate ICD therapy in primary prevention patients with ischemic cardiomyopathy persists for up to seven years, supporting the clinical indication for device replacement.

Cite This Study

Alsheikh‐Ali et al. (2008) studied this question.

synapsesocial.com/papers/6a881305ce59b4d55bcf07c2 https://doi.org/10.1111/j.1540-8167.2008.01111.x

Topics

Ventricular arrhythmias Cardiac device therapy Cardiomyopathy Women and heart disease

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February 13, 2008Journal of Cardiovascular Electrophysiology

Time‐Dependence of Appropriate Implantable Defibrillator Therapy in Patients with Ischemic Cardiomyopathy

View Full Paper

Ask AI

Bookmark

Why the study?

Does the risk of appropriate ICD therapy persist over time in primary prevention patients with prior MI and LVEF ≤35%?

Population

525 patients with prior myocardial infarction and reduced left ventricular ejection fraction who received an…

Design

Cohort

Follow-up

up to 7 years

Authors

AAAlawi Alsheikh‐AliElectrophysiology MHMichael HomerReproductive Science Center PMPrasad MaddukuriSaint Vincent Hospital

Discussion

Member takes

Implication

Risk persists at 6-11% yearly beyond year 1 in ischemic cardiomyopathy; leaves open whether findings justify routine generator replacement.

Structured PICO

Does the risk of appropriate ICD therapy persist over time in primary prevention patients with prior MI and LVEF ≤35%?

Population

Intervention

Implantable cardioverter-defibrillator (ICD) for primary prevention

Outcome

Incidence and time-dependence of first appropriate ICD therapy for ventricular arrhythmia (VA) and rapid VA (cycle length ≤260 ms)hard clinical

The risk of appropriate ICD therapy in primary prevention patients with ischemic cardiomyopathy persists for up to seven years, supporting the clinical indication for device replacement.

Cite This Study

Alsheikh‐Ali et al. (2008) studied this question.

synapsesocial.com/papers/6a881305ce59b4d55bcf07c2 https://doi.org/10.1111/j.1540-8167.2008.01111.x

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Topics

Ventricular arrhythmias Cardiac device therapy Cardiomyopathy Women and heart disease

View Full Paper

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