Population
13 inbred dogs (6 with neonatally-induced coarctation hypertension, 7 littermate controls)
Comparison
Neonatally-induced coarctation hypertension and… vs Littermate controls without coarctation
Design
Preclinical
Follow-up
1-12 months
Authors
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Does not implicate circulating renin modifiers in canine coarctation hypertension; leaves open alternative mechanisms.
Circulating modifiers of the renin reaction do not appear to play a role in the genesis or early maintenance of neonatally-induced coarctation hypertension in a canine model.
Bagby et al. (1981) studied this question.
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