Key result
One-anastomosis and Roux-en-Y gastric bypass showed significantly higher weight loss compared to laparoscopic sleeve gastrectomy at 9 and 24 months post-surgery, respectively (p < 0.05).
Why the study?
Mid-term results after bariatric surgery remain a major concern due to repetitive weight fluctuations, prompting investigation into key time points of weight changes and 5-year weight loss outcomes across three surgical types.
Does the type of bariatric surgery (LSG, RYGB, OAGB) affect the trajectory of weight loss and weight regain over 5 years in patients with morbid obesity?
Population
2,567 participants with morbid obesity
Comparison
LSG vs RYGB vs OAGB
Design
Retrospective cohort study
Follow-up
5 years
Authors
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Observational data associate OAGB/RYGB with greater early weight loss than LSG; leaves open long-term trajectories and practice implications in morbid obesity.
Cohort (n=2,567)
No
Does the type of bariatric surgery (LSG, RYGB, OAGB) affect the trajectory of weight loss and weight regain over 5 years in patients with morbid obesity?
p-value: p=<0.05
One-anastomosis gastric bypass provides the fastest and highest weight loss, whereas laparoscopic sleeve gastrectomy is associated with earlier weight plateau and regain over a 5-year period.
Hatami et al. (2023) conducted a cohort in morbid obesity (n=2,567). One-anastomosis gastric bypass (OAGB) and Roux-en-Y gastric bypass (RYGB) vs. Laparoscopic sleeve gastrectomy (LSG) was evaluated on Excessive weight loss (%EWL) and total weight loss (%TWL) (p=<0.05). One-anastomosis and Roux-en-Y gastric bypass showed significantly higher weight loss compared to laparoscopic sleeve gastrectomy at 9 and 24 months post-surgery, respectively (p < 0.05).
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