Why the study?
Does oral theophylline prevent tilt-induced and spontaneous vasodepressor syncope in affected patients?
Population
Patients with vasodepressor syncope, mean age 40.7 +/- 18.1 years.
Comparison
Oral theophylline vs Baseline (before treatment)
Design
Cohort
Follow-up
10.7 +/- 6.1 months
Authors
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May support theophylline in vasodepressor syncope; leaves open efficacy confirmation in randomized trials.
Does oral theophylline prevent tilt-induced and spontaneous vasodepressor syncope in affected patients?
Low-dose oral theophylline may prevent tilt-induced and spontaneous vasodepressor syncope, though tolerability is a significant limiting factor.
Steven D. Nelson (1991) studied this question.
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