Key result
Higher neutrophil/lymphocyte ratio was significantly associated with coronary artery disease (OR 1.227; 95% CI 1.016-1.482; P<0.05).
Why the study?
Inflammation contributes to CAD, but a systematic comparison of inflammatory parameters like NLR, MLR, and PLR across different stages of CAD was needed.
Are inflammatory markers (NLR, MLR, PLR) associated with different stages of coronary artery disease?
Population
513 patients who had undergone coronary angiography
Comparison
Normal coronary vs CA vs CCS vs AMI groups
Design
Retrospective observational study
Authors
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NLR may aid CAD risk stratification by acuity; leaves open its added value beyond standard markers in prospective cohorts.
Observational (n=513)
Are inflammatory markers (NLR, MLR, PLR) associated with different stages of coronary artery disease?
Odds Ratio: 1.227 (95% CI 1.016–1.482)
p-value: p=<0.05
The neutrophil/lymphocyte ratio is significantly associated with the presence and severity of coronary artery disease, particularly acute myocardial infarction.
Du et al. (2022) conducted an observational in Coronary artery disease (n=513). Neutrophil/lymphocyte ratio (NLR) was evaluated on Presence of coronary artery disease (OR 1.227, 95% CI 1.016-1.482, p=<0.05). Higher neutrophil/lymphocyte ratio was significantly associated with coronary artery disease (OR 1.227; 95% CI 1.016-1.482; P<0.05).
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