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March 29, 2015Angiology

Neutrophil to Lymphocyte Ratio and the Extent of Coronary Artery Disease

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Why the study?

Is the neutrophil to lymphocyte ratio associated with the prevalence and severity of coronary artery disease in patients undergoing coronary angiography?

Population

3,738 consecutive patients undergoing elective or urgent coronary angiography

Comparison

Higher neutrophil to lymphocyte ratio (NLR) vs Lower neutrophil to lymphocyte ratio (NLR)

Design

Cross-sectional

Authors

MVMonica VerdoiaLBLucia BarbieriGGGabriella Di Giovine

Discussion

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Overview

NLR association with CAD prevalence/severity is hypothesis-generating; leaves open incremental value in prospective risk models before any clinical use.

Structured PICO

Is the neutrophil to lymphocyte ratio associated with the prevalence and severity of coronary artery disease in patients undergoing coronary angiography?

P
Population
3,738 consecutive patients undergoing elective or urgent coronary angiography
I
Intervention
Higher neutrophil to lymphocyte ratio (NLR)
C
Comparator
Lower neutrophil to lymphocyte ratio (NLR)
O
Outcome
Prevalence and extent of coronary artery disease (CAD)surrogate

Higher neutrophil to lymphocyte ratio is independently associated with increased prevalence and severity of coronary artery disease in patients undergoing coronary angiography.

Cite This Study

Verdoia et al. (2015) studied this question.

synapsesocial.com/papers/6a73c0cd46cd4472af69ef5chttps://doi.org/10.1177/0003319715577529
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