April 1, 1998European Journal of Cardio-Thoracic SurgeryOpen Access

High-risk mitral valve replacement in severe pulmonary hypertension—30 years experience1

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Why the study?

Does mitral valve replacement improve survival and functional status in patients with severe pulmonary hypertension?

Population

382 patients with severe pulmonary hypertension undergoing mitral valve replacement out of a total 2316 MVR…

Comparison

Mitral valve replacement vs Routine elective mitral valve replacement in…

Design

Cohort

Follow-up

mean 8.4 +/- 0.2 years

Authors

RCRobert CesnjevarFriedrich-Alexander-Universität Erlangen-Nürnberg RFRichard FeyrerCentral Military Hospital FWFriedrich WaltherUniversitätsklinikum Erlangen

Discussion

Member takes

Implication

Early mortality risk warrants perioperative caution in severe PH; cohort data extend late-survival observations but leave randomized confirmation open.

Structured PICO

Does mitral valve replacement improve survival and functional status in patients with severe pulmonary hypertension?

Population

382 patients with severe pulmonary hypertension (pulmonary artery pressure > 50 mmHg; pulmonary vascular resistance 690 +/- 46 dyn/s per m2) undergoing mitral valve replacement out of a total 2316 MVR patients over 30 years.

Intervention

Mitral valve replacement (336 mechanical and 46 biological devices)

Comparator

Routine elective mitral valve replacement in patients without severe pulmonary hypertension

Outcome

Early mortality and late mortalityhard clinical

Mitral valve replacement in patients with severe pulmonary hypertension carries a high early mortality risk but offers good long-term survival and functional improvement comparable to patients without pulmonary hypertension.

Cite This Study

Cesnjevar et al. (1998) studied this question.

synapsesocial.com/papers/6a884fefc0c64b7dddeb44f4 https://doi.org/10.1016/s1010-7940(98)00042-6

Topics

Mitral valve intervention

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Implication

Early mortality risk warrants perioperative caution in severe PH; cohort data extend late-survival observations but leave randomized confirmation open.

High-risk mitral valve replacement in severe pulmonary hypertension—30 years experience1

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

High-risk mitral valve replacement in severe pulmonary hypertension—30 years experience1

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider