Key result
Mitral valve replacement in patients with severe pulmonary hypertension was safe, with 0% mortality at 3 months and significant improvements in mean pulmonary artery pressure.
Why the study?
Does conventional surgical MVR improve early hemodynamic outcomes safely in patients with rheumatic mitral stenosis and severe pulmonary hypertension compared to those with mild pulmonary hypertension?
Population
40 patients with rheumatic mitral stenosis indicated for elective MVR, mean age 32.40 years, 17 male and 23…
Comparison
Conventional surgical mitral valve replacement… vs Conventional surgical mitral valve replacement…
Design
Cohort
Follow-up
3 months
Authors
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May support MVR safety in severe PH; leaves open need for RCTs versus milder cases.
Observational (n=40)
Yes
Does conventional surgical MVR improve early hemodynamic outcomes safely in patients with rheumatic mitral stenosis and severe pulmonary hypertension compared to those with mild pulmonary hypertension?
Conventional surgical mitral valve replacement is safe and effective in improving hemodynamics in patients with rheumatic mitral stenosis, even in the presence of severe pulmonary hypertension.
Abdellatif et al. (2016) conducted an observational in Rheumatic mitral stenosis with pulmonary hypertension (n=40). Severe pulmonary hypertension (mPAP > 55 mmHg) vs. Mild pulmonary hypertension (mPAP 26-40 mmHg) was evaluated on Duration of postoperative mechanical ventilation and improvement in mean pulmonary artery pressure. Mitral valve replacement in patients with severe pulmonary hypertension was safe, with 0% mortality at 3 months and significant improvements in mean pulmonary artery pressure.
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