Why the study?
Does cardiac surgery improve survival and symptoms in patients with mitral valve disease and extreme pulmonary hypertension compared to no operation?
Population
48 patients with extreme pulmonary hypertension out of a larger cohort of 586 patients with mitral valve…
Comparison
Cardiac surgery vs No operation (natural history)
Design
Cohort
Follow-up
mean 5.8 ± 0.6 years for surgical survivors
Authors
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Surgery may improve survival versus no operation in extreme PH despite high risk; leaves open optimal selection in contemporary mitral cohorts.
Does cardiac surgery improve survival and symptoms in patients with mitral valve disease and extreme pulmonary hypertension compared to no operation?
Despite high operative mortality, particularly for valve replacement, cardiac surgery offers significant long-term survival and symptomatic benefits over the poor natural history of unoperated mitral valve disease with extreme pulmonary hypertension.
Ward et al. (1975) studied this question.
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