Why the study?
Does captopril compared to nicardipine differentially affect renal blood flow and sympathetic nerve activity in conscious renal hypertensive rabbits?
Does captopril compared to nicardipine differentially affect renal blood flow and sympathetic nerve activity in conscious renal hypertensive rabbits?
Captopril and nicardipine have differing effects on renal blood flow in renal hypertensive rabbits, likely due to differences in sympathetic nerve activity and angiotensin II levels.
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Captopril may better sustain RBF than nicardipine in renal hypertensive models; leaves open sympathetic mechanisms and human translation.
Kumagai et al. (1995) studied this question.
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