Population
Cultured bullfrog sympathetic ganglion cells (2- to 10-day-old)
Comparison
Muscarine applied to the membrane outside the… vs Baseline/control and atropine (1 microM) block
Design
Preclinical
Authors
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Muscarine may modulate resting potential and slow IPSPs via background K+ channels; hypothesis-generating for mammalian autonomic regulation.
Muscarine enhances the activity of a voltage-independent background K+ channel in bullfrog sympathetic ganglion cells, which may contribute to resting membrane potential and slow inhibitory postsynaptic potentials.
Koyano et al. (1992) studied this question.
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