Population
Cultured chicken skeletal muscle cells (myotubes)
Comparison
Suppression of cofilin expression using… vs Developed myotubes vs early phase myotubes
Design
Preclinical
Authors
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Cofilin is critical for early myofibrillogenesis; hypothesis-generating for actin-related myopathies but leaves open mammalian validation and clinical relevance.
Cofilin plays a critical role in the regulation of actin assembly during the early process of myofibrillogenesis in skeletal muscle cells.
Miyauchi‐Nomura et al. (2012) studied this question.
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