Why the study?
Does low dose aspirin reduce thrombus formation and improve microcirculatory perfusion in a rat model of microvascular surgery?
Population
56 male Wistar rats
Comparison
Aspirin (5 mg/kg systemically) vs Saline treatment
Design
Preclinical, Assigned in equal numbers to groups
Follow-up
6 hours (for microcirculation measurement)
Authors
Loading...
Reduces venous thrombosis in rat microsurgery models; leaves open translation to human free-flap outcomes.
Does low dose aspirin reduce thrombus formation and improve microcirculatory perfusion in a rat model of microvascular surgery?
Low dose aspirin inhibits anastomotic venous thrombosis and improves microcirculatory perfusion in a rat model of microvascular surgery.
Peter et al. (1997) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: