Population
Cardiac microvascular endothelial cells isolated from rat ventricular muscle and cultured on thin sheets of…
Comparison
Static stretch for 24 hours (by 5%, 10%, and 15%) vs Control, nonstretched cells
Design
Preclinical
Follow-up
24 hours
Authors
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Leaves open whether stretch-enhanced IK alters endothelial function or angiogenesis in vivo; no clinical implications yet.
Mechanical stretch significantly increases delayed rectifier K+ currents and shifts their activation voltage in cardiac microvascular endothelial cells, potentially regulating resting potential and capillary growth.
Fan et al. (1999) studied this question.
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