Why the study?
Does cigarette smoking reduce the age at onset of a first non-fatal myocardial infarction?
Population
2445 patients experiencing their first non-fatal myocardial infarction
Comparison
Cigarette smoking vs Non-smokers and ex-smokers
Design
Cohort
Follow-up
more than 2 years
Authors
Loading...
May support earlier risk stratification among smokers; leaves open whether cessation reverses the acceleration in prospective trials.
Does cigarette smoking reduce the age at onset of a first non-fatal myocardial infarction?
Active smoking is associated with a striking inverse dose-response effect on the age at onset of first myocardial infarction, reducing it by up to 8.7 years in heavy smokers.
Gottlieb et al. (1994) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: