Why the study?
Does cigarette smoking increase the risk of nonfatal myocardial infarction?
Population
Patients with nonfatal myocardial infarction (cases) and controls
Comparison
Cigarette smoking (one and two packs per day) vs Non-smokers (implied reference group)
Design
Case-control
Authors
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May reinforce cessation counseling in low-risk groups; leaves open causal confirmation from observational design.
Does cigarette smoking increase the risk of nonfatal myocardial infarction?
Cigarette smoking is associated with a dose-dependent increased risk of nonfatal myocardial infarction, with the strongest association observed in younger individuals and those with a low baseline risk score.
Miettinen et al. (1976) studied this question.
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