Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 1, 2017Journal of Diabetes InvestigationOpen Access

Grading effect of abnormal glucose status on arterial stiffness and a new threshold of 2‐h post‐load glucose based on a Chinese community study

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does abnormal glucose status increase the risk of arterial stiffness in a community population?

Population

4,851 individuals from a Chinese community

Comparison

Various glucose metabolic statuses vs Normal glucose tolerance

Design

Cross-sectional

Authors

ZLZhike LiuPeking UniversityKWKe‐Ye WuSouthern University of Science and TechnologyXDXiaotong DaiBeijing Sport University

Discussion

Loading...

Member takes

Implication

Highlights the potential vascular risk of early glucose intolerance; leaves open whether targeting a 6.

Structured PICO

Does abnormal glucose status increase the risk of arterial stiffness in a community population?

P
Population
4,851 individuals from a Chinese community
I
Intervention
Various glucose metabolic statuses (isolated impaired fasting glucose, isolated impaired glucose tolerance, combined glucose intolerance, newly diagnosed diabetes mellitus)
C
Comparator
Normal glucose tolerance
O
Outcome
Arterial stiffness measured as brachial-ankle pulse wave velocitysurrogate

Abnormal glucose metabolism, even at pre-diabetic stages, is associated with increased arterial stiffness, with a potential 2-hour post-load glucose threshold of 6.14 mmol/L.

Cite This Study

Liu et al. (2017) studied this question.

synapsesocial.com/papers/6a887b59b98a632b5e4fe281https://doi.org/10.1111/jdi.12741
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Deleterious Impact of “High Normal” Glucose Levels and Other Metabolic Syndrome Components on Arterial Endothelial Function and Intima-Media Thickness in Apparently Healthy Chinese Subjects: The CATHAY Study2004 · 111 citations
  2. 2Association between prediabetes and risk of cardiovascular disease and all cause mortality: systematic review and meta-analysis2016 · 1,049 citations
  3. 3Association Between Arterial Stiffness and Atherosclerosis2001 · 1,145 citations
  4. 4Ventricular and Vascular Stiffening in Aging and Hypertension2015 · 34 citations
  5. 5Increased arterial stiffness in healthy subjects with high-normal glucose levels and in subjects with pre-diabetes2011 · 128 citations