Key result
Elevated 1-h post-challenge plasma glucose was significantly correlated with increased brachial-ankle pulse wave velocity (r = 0.340, P < 0.0001) in subjects with normal glucose tolerance.
Why the study?
Does elevated 1-h post-challenge plasma glucose predict arterial stiffness in subjects with normal glucose tolerance?
Population
2059 subjects with normal glucose tolerance from Takasaki city, Japan
Comparison
Higher 1-h post-challenge plasma glucose levels… vs Lower 1-h post-challenge plasma glucose levels
Design
Cross-sectional
Authors
Loading...
May mark early stiffness in normoglycemia; hypothesis-generating and requires longitudinal confirmation before clinical use.
Cross-Sectional (n=2,059)
No
Does elevated 1-h post-challenge plasma glucose predict arterial stiffness in subjects with normal glucose tolerance?
Effect estimate: r = 0.340
Absolute Event Rate: 1473% vs 1275%
p-value: p=< 0.0001
Elevated 1-hour post-challenge plasma glucose is associated with increased arterial stiffness in individuals with normal glucose tolerance, suggesting it may be an early risk marker.
Niijima et al. (2012) conducted a cross-sectional in Normal glucose tolerance (n=2,059). Elevated 1-h post-challenge plasma glucose vs. Lower 1-h plasma glucose (< 8.56 mmol/l) was evaluated on Brachial-ankle pulse wave velocity (r = 0.340, p=< 0.0001). Elevated 1-h post-challenge plasma glucose was significantly correlated with increased brachial-ankle pulse wave velocity (r = 0.340, P < 0.0001) in subjects with normal glucose tolerance.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: