Why the study?
Can echocardiographic criteria accurately detect congestive heart failure in postinfarction rats without invasive hemodynamic evaluation?
Population
Postinfarction and sham-operated rats evaluated 6 months after myocardial infarction induction. The study…
Comparison
Echocardiographic evaluation using 6 variables… vs Pathological criteria of congestive heart…
Design
Preclinical
Follow-up
6 months
Authors
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May aid non-invasive CHF rat selection for research; leaves open human validation before any clinical consideration.
Can echocardiographic criteria accurately detect congestive heart failure in postinfarction rats without invasive hemodynamic evaluation?
Echocardiographic analysis using a specific discriminant function can accurately predict congestive heart failure in postinfarction rats, facilitating non-invasive animal selection for CHF studies.
Martinez et al. (2011) studied this question.
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