Life-long clinical outcome after the first myocardial revascularization procedures: 40-year follow-up after coronary artery bypass grafting and percutaneous coronary intervention in Rotterdam
Why the study?
The study evaluated life-long outcomes up to 40 years among the first consecutive patients treated with venous CABG or balloon angioplasty PCI at a single centre.
What are the life-long survival and repeat revascularization rates in patients undergoing the earliest CABG and PCI procedures?
Population
1041 venous CABG patients and 856 PCI patients at a single centre
Comparison
Venous CABG vs PCI with balloon angioplasty cohorts
Design
Single-centre observational cohort study
Follow-up
Median 39 years (CABG) and 33 years (PCI)
Authors
Discussion
Loading...
Member takes
Implication
Very long-term survival after early venous CABG or balloon PCI is limited with frequent repeat procedures; leaves open durability of modern techniques.
Key Points
- To evaluate the long-term clinical outcomes and survival across up to 40 years of follow-up in the earliest cohorts of patients treated with venous CABG or balloon angioplasty PCI at a single center.
- Analyzed consecutive patients undergoing venous CABG (n = 1,041; 1971–1980) or balloon angioplasty PCI (n = 856; 1980–1985) at a single center.
- Follow-up was completed in 98% of CABG patients (median 39 years, range 36–46) and 97% of PCI patients (median 33 years, range 32–36).
- Cumulative survival rates after CABG were 77% at 10 years, 39% at 20 years, 14% at 30 years, and 4% at 40 years, yielding an estimated life expectancy of 18 years.
- Cumulative survival rates after PCI were 78% at 10 years, 47% at 20 years, 21% at 30 years, and 12% at 35 years, yielding an estimated life expectancy of 17 years.
- Repeat revascularization was performed in 36% of patients in the CABG cohort and 57% of patients in the PCI cohort.
Structured PICO
What are the life-long survival and repeat revascularization rates in patients undergoing the earliest CABG and PCI procedures?
P
Population
1,897 patients undergoing their first myocardial revascularization procedure at a single center in Rotterdam, including 1,041 patients undergoing venous CABG (median age 53, 82% multivessel CAD) and 856 patients undergoing PCI with balloon angioplasty (median age 57, 37% multivessel CAD).
I
Intervention
Venous coronary artery bypass grafting (CABG) performed between 1971 and 1980, or percutaneous coronary intervention (PCI) with balloon angioplasty performed between 1980 and 1985.
C
Comparator
null
O
Outcome
Cumulative survival rates and estimated life expectancy up to 40 years.hard clinical
Life-long follow-up of the earliest CABG and PCI cohorts demonstrates substantial long-term survival, with estimated life expectancies of 18 and 17 years, respectively.
Cite This Study
Milojevic et al. (2019) studied this question.