Population
Longitudinal muscle isolated from the guinea pig ileum
Comparison
Acetylcholine, varying calcium concentrations… vs Different concentrations of calcium and…
Design
Preclinical
Authors
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These intestinal smooth muscle findings should not alter cardiovascular practice; leaves open mechanistic parallels for vascular calcium-potassium regulation.
Extracellular calcium ions appear to react with stabilizing and storage sites in the membrane, modulating acetylcholine-induced contraction and potassium efflux in intestinal smooth muscle.
Hurwitz et al. (1967) studied this question.
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