Why the study?
Does lisinopril improve blood pressure control and tolerability compared to nifedipine retard in patients with essential hypertension?
Does lisinopril improve blood pressure control and tolerability compared to nifedipine retard in patients with essential hypertension?
Lisinopril and nifedipine retard are equally effective for controlling essential hypertension, but lisinopril is significantly better tolerated.
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Lisinopril was associated with similar BP reduction but fewer adverse effects than nifedipine; observational data leave open the need for RCTs to guide practice.
Richardson et al. (1987) studied this question.