BMS-180448 exerts significant vasorelaxant activity in rat aorta via multiple mechanisms including blockade of extracellular Ca2+ influx and activation of the adenylate cyclase and nitric oxide pathway.
No takes yet. Share an insight, caveat, or question.
May guide preclinical vasodilator development; leaves open human translation and clinical testing.
Park et al. (2003) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: