Why the study?
Gallstone disease is increasing globally and carries various complications, but its relationship with CVD and cancer mortality required systematic evaluation.
Does gallstone disease increase the risk of mortality from cardiovascular disease and cancer?
Population
Up to 562,625 participants across pooled studies
Comparison
Individuals with gallstone disease vs without gallstone disease
Design
Systematic review and meta-analysis
Authors
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GD associated with higher CVD (RR 1.29) and cancer mortality; leaves open whether targeted interventions improve outcomes in observational data.
Does gallstone disease increase the risk of mortality from cardiovascular disease and cancer?
Gallstone disease is significantly associated with an elevated risk of mortality from cardiovascular disease and cancer, suggesting a need for targeted interventions in this population.
Rahimi et al. (2024) studied this question.
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