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January 1, 2009Congestive Heart Failure

Optimization of Cardiac Resynchronization Therapy: Echocardiographic vs Semiautomatic Device Algorithms

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Why the study?

Does an IEGM-based method reliably calculate optimal AV and VV delays compared to an ECHO-based method in male patients with congestive heart failure and a resynchronization device?

Population

10 male patients with congestive heart failure implanted with a St Jude Medical resynchronization device

Comparison

Intracardiac electrogram-based method to… vs Doppler echocardiographic-based method to…

Design

Cross-sectional

Authors

MAMatteo AnselminoMAMarina AntoliniCAClaudia Amellone

Discussion

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Overview

IEGM may simplify AV/VV optimization in CRT; leaves open prospective outcome trials versus echocardiography.

Structured PICO

Does an IEGM-based method reliably calculate optimal AV and VV delays compared to an ECHO-based method in male patients with congestive heart failure and a resynchronization device?

P
Population
10 male patients with congestive heart failure implanted with a St Jude Medical resynchronization device
I
Intervention
Intracardiac electrogram (IEGM)-based method to calculate optimal atrioventricular (AV) and interventricular (VV) delays
C
Comparator
Doppler echocardiographic (ECHO)-based method to calculate optimal AV and VV delays
O
Outcome
Optimal atrioventricular (AV) and interventricular (VV) delayssurrogate

An IEGM-based algorithm provides comparable optimal AV and VV delays to standard echocardiography for cardiac resynchronization therapy optimization.

Limitations

  • Preliminary data

Cite This Study

Anselmino et al. (2009) studied this question.

synapsesocial.com/papers/6a894588dc4e0776fedeef98https://doi.org/10.1111/j.1751-7133.2008.00036.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute Evaluation of Programmer‐Guided AV/PV and VV Delay Optimization Comparing an IEGM Method and Echocardiogram for Cardiac Resynchronization Therapy in Heart Failure Patients and Dual‐Chamber ICD Implants2006 · 109 citations
  2. 2Estimation of the Optimal VV Delay by an IEGM‐Based Method in Cardiac Resynchronization Therapy2007 · 29 citations
  3. 3Cardiac Resynchronization in Chronic Heart Failure2002 · 4,613 citations
  4. 4long-term clinical effect of hemodynamically optimized cardiac resynchronization therapy in patients with heart failure and ventricular conduction delay2002 · 1,031 citations
  5. 5Sequential Versus Simultaneous Biventricular Resynchronization for Severe Heart Failure2002 · 500 citations