Key result
The IEGM-based method for optimizing interventricular delay closely correlated with the standard echocardiographic method in prospective (concordance 0.99) and retrospective (concordance 0.98) cohorts.
Why the study?
Does an IEGM-based method for determining optimal VV delay perform similarly to an ECHO-based method in patients receiving cardiac resynchronization therapy?
Population
72 patients receiving cardiac resynchronization therapy
Comparison
Intracardiac electrogram-based method for… vs Echocardiographic-based method using aortic…
Design
Cohort
Authors
Loading...
May offer a faster alternative to echocardiography for VV optimization in CRT; leaves open whether it improves outcomes in randomized trials.
Observational (n=72)
Does an IEGM-based method for determining optimal VV delay perform similarly to an ECHO-based method in patients receiving cardiac resynchronization therapy?
Effect estimate: concordance correlation coefficient 0.99 (95% CI lower limit of 98%)
Absolute Event Rate: 23.9% vs 24.3%
An IEGM-based method for optimizing VV delay in cardiac resynchronization therapy provides highly concordant results with the traditional, more time-consuming echocardiographic AVTI method.
Min et al. (2007) conducted an observational in Cardiac resynchronization therapy (n=72). Intracardiac electrogram (IEGM)-based VV method vs. Echocardiographic (ECHO) aortic velocity time integral (AVTI) method was evaluated on Maximum aortic velocity time integral (AVTI) (concordance correlation coefficient 0.99, 95% CI lower limit of 98%). The IEGM-based method for optimizing interventricular delay closely correlated with the standard echocardiographic method in prospective (concordance 0.99) and retrospective (concordance 0.98) cohorts.