Why the study?
Does hypothermic arrest with cold blood at 17 C improve preservation of myocardial energy substances compared to potassium citrate arrest at 37 C in canine hearts?
Population
Canine hearts (preclinical model)
Comparison
Hypothermic arrest with cold blood at 17 C vs Potassium citrate arrest at 37 C
Design
Preclinical
Follow-up
60 minutes
Authors
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Hypothermia may better preserve myocardial ATP than normothermic potassium arrest in dogs; leaves open applicability to clinical cardioplegia.
Does hypothermic arrest with cold blood at 17 C improve preservation of myocardial energy substances compared to potassium citrate arrest at 37 C in canine hearts?
Selective hypothermic arrest preserves myocardial energy stores (ATP, glycogen) significantly better than normothermic potassium citrate arrest in canine hearts.
Gott et al. (1962) studied this question.
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