What does this research mean for the field?

Probiotic interventions significantly reduce triglycerides, total cholesterol, and LDL-C, while modestly increasing HDL-C, supporting their use as an adjunctive therapy for dyslipidemia management. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the efficacy of probiotic interventions on serum lipid profiles, including triglycerides, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol.

August 22, 2026Critical Reviews in Food Science and Nutrition

Effects of probiotic intervention on serum lipid profiles: current evidence from systematic review and meta-analysis of randomized controlled trials

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Authors

PAPattarachon Apisitwittaya RIRatchanon Inpan MTMingkwan Na Takuathung

Discussion

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Overview

Meta-analysis of randomized controlled trials shows probiotic supplementation significantly improves serum lipid levels, indicating its potential as an adjunctive therapy for dyslipidemia.

Key Points

To evaluate the efficacy of probiotic interventions on serum lipid profiles, including triglycerides, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol.
Systematic search conducted across PubMed, Embase, Scopus, and Cochrane Library through February 2025.
Meta-analysis pooled data from 155 randomized controlled trials comprising 9,906 participants using a random-effects model to calculate mean differences.
Probiotic intervention significantly decreased triglycerides (MD = -10.83 mg/dL, p < 0.0001), total cholesterol (MD = -8.46 mg/dL, p < 0.0001), and LDL-C (MD = -5.83 mg/dL, p < 0.0001).
Probiotic supplementation modestly increased HDL-C levels compared with controls (MD = 1.28 mg/dL, p < 0.0001).

Cite This Study

Apisitwittaya et al. (2026) studied this question.

synapsesocial.com/papers/6a895ed9ca7ade938187d005 https://doi.org/10.1080/10408398.2026.2714684

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August 22, 2026Critical Reviews in Food Science and Nutrition

Effects of probiotic intervention on serum lipid profiles: current evidence from systematic review and meta-analysis of randomized controlled trials

View Full Paper

Ask AI

Bookmark

Authors

PAPattarachon Apisitwittaya RIRatchanon Inpan MTMingkwan Na Takuathung

Discussion

Member takes

Overview

Meta-analysis of randomized controlled trials shows probiotic supplementation significantly improves serum lipid levels, indicating its potential as an adjunctive therapy for dyslipidemia.

Key Points

To evaluate the efficacy of probiotic interventions on serum lipid profiles, including triglycerides, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol.
Systematic search conducted across PubMed, Embase, Scopus, and Cochrane Library through February 2025.
Meta-analysis pooled data from 155 randomized controlled trials comprising 9,906 participants using a random-effects model to calculate mean differences.
Probiotic intervention significantly decreased triglycerides (MD = -10.83 mg/dL, p < 0.0001), total cholesterol (MD = -8.46 mg/dL, p < 0.0001), and LDL-C (MD = -5.83 mg/dL, p < 0.0001).
Probiotic supplementation modestly increased HDL-C levels compared with controls (MD = 1.28 mg/dL, p < 0.0001).

Cite This Study

Apisitwittaya et al. (2026) studied this question.

synapsesocial.com/papers/6a895ed9ca7ade938187d005 https://doi.org/10.1080/10408398.2026.2714684

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