Why the study?
Do various pharmacological and physiological stimuli differentially affect active and inactive plasma renin activity in normal subjects?
Population
Normal subjects
Design
Other
Follow-up
up to 4 days
Authors
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Active and inactive PRA respond differently to stimuli; extends renin regulation insights but should not yet alter clinical interpretation.
Do various pharmacological and physiological stimuli differentially affect active and inactive plasma renin activity in normal subjects?
The mechanisms controlling active and inactive renin are distinct, and neither renal nor plasma kallikrein appears consistently involved in the in vivo activation of inactive renin.
Nakamaru et al. (1982) studied this question.
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