Why the study?
What are the secretion patterns of active and inactive renin in response to various stimuli in normal subjects and hypertensive patients?
What are the secretion patterns of active and inactive renin in response to various stimuli in normal subjects and hypertensive patients?
The time constants for the secretion or release of active and inactive renin in humans are of different orders of magnitude, with active renin responding more acutely to stimuli.
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Supports distinct secretion kinetics for active vs inactive renin; hypothesis-generating and should not yet change practice.
Kappelgaard et al. (1978) studied this question.
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