May 1, 1978Clinical Science

Control of Enzymatically Inactive Renin in man under Various Pathological Conditions: Implications for the Interpretation of Renin Measurements in Peripheral and Renal Venous Plasma

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Population

Patients with essential hypertension, renovascular hypertension, primary aldosteronism, adrenal…

Design

Cross-sectional

Authors

FDF. H. M. DerkxGeneral / Preventive / Lipids GWG. J. WentingErasmus MC AVA J Man in 't VeldErasmus MC

Discussion

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Implication

Peripheral renin ratios may aid renovascular hypertension evaluation; leaves open diagnostic utility pending prospective validation.

Structured PICO

Population

Patients with essential hypertension (n=22), renovascular hypertension (n=14 to 17), primary aldosteronism (n=12), adrenal insufficiency (n=6), bilateral nephrectomy (n=12), and control subjects (n=13).

Outcome

Active and inactive renin levels in peripheral and renal venous plasmasurrogate

The kidney appears to control both the total quantity of circulating renin and its degree of activation, which has implications for interpreting renin measurements in various pathological conditions.

Cite This Study

Derkx et al. (1978) studied this question.

synapsesocial.com/papers/6a701f793ce530166bc2bce4 https://doi.org/10.1042/cs0540529

Topics

Hypertension management

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Control of Enzymatically Inactive Renin in man under Various Pathological Conditions: Implications for the Interpretation of Renin Measurements in Peripheral and Renal Venous Plasma

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Control of Enzymatically Inactive Renin in man under Various Pathological Conditions: Implications for the Interpretation of Renin Measurements in Peripheral and Renal Venous Plasma

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Topics

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