Population
Anesthetized hypophysectomized, cortisone-treated dogs undergoing water diuresis via 2.5% dextrose infusion
Comparison
Isoproterenol added to left renal artery infusate vs Right kidney and left kidney before/after…
Design
Preclinical
Authors
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Suggests beta-adrenergic effects on renal water handling in dogs; leaves open human applicability.
Beta-adrenergic stimulation with isoproterenol decreases proximal tubular sodium reabsorption in dogs, likely via direct action on the renal tubule.
Gill et al. (1971) studied this question.
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