Why the study?
Does progressive treadmill training alter intrinsic SA node automaticity or beta-adrenergic responsiveness in male Sprague-Dawley rats?
Population
Male Sprague-Dawley rats
Comparison
12-16 week program of progressive treadmill… vs Sedentary (cage confined) rats
Design
Preclinical
Follow-up
12-16 weeks
Authors
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Supports intrinsic SA node adaptations in exercise bradycardia in rats; leaves open translation to human athletes or patients.
Does progressive treadmill training alter intrinsic SA node automaticity or beta-adrenergic responsiveness in male Sprague-Dawley rats?
Training-induced bradycardia in rats is driven by changes in intrinsic SA node automaticity rather than altered beta-adrenergic responsiveness.
SCHAEFER et al. (1992) studied this question.
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